Serum Sickness in Rabbits
نویسندگان
چکیده
1. The injection of a single large dose of normal horse serum into rabbits results in the appearance 3 to 8 days later of erythematous and edematous reactions on the ears in 68.9 per cent of the animals. 2. The injections may be given by any of several routes and reactions appear when the site of injection is definitely distant from the ears. 3. Injections of various antisera into rabbits cause the appearance of similar reactions. 4. These reactions can be considered as manifestations of serum sickness in rabbits.
منابع مشابه
Serum Sickness in Rabbits I. Manifestations of Serum Sickness
The occurrence in man of reactions subsequent to a first injection of certain foreign proteins has long been recognized and, following the general use of antisera of various types, these reactions were thoroughly studied by von Pirquet and Schick (1) who gave the name serum sickness or serum disease to this phenomenon. I t was possible to study it quite extensively as it occurs in man. However,...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 55 شماره
صفحات -
تاریخ انتشار 2003